At Lonerock Clinic, we offer Spravato® (esketamine) in a medically supervised setting to support adults with treatment-resistant depression.


Spravato® (esketamine) is a prescription nasal spray derived from ketamine, designed specifically for adults with treatment-resistant depression (TRD). Unlike traditional antidepressants that target serotonin and can take weeks to work, Spravato® acts on glutamate receptors in the brain helping restore connections between nerve cells and improving mood more rapidly.
Each treatment is administered under medical supervision in a calm, supportive environment. Patients relax during their session while our care team monitors progress and ensures safety throughout. Combined with ongoing therapy or medication management, Spravato® can provide lasting relief and renewed emotional balance.
Spravato® offers new hope for individuals who haven’t responded to traditional antidepressants. With its innovative approach and medically supervised treatments, it helps patients experience real improvement in mood, energy, and outlook.
Your Spravato® journey at Lonerock Clinic begins with a personalized evaluation to confirm eligibility and tailor your care plan. Each session is designed to maximize comfort, safety, and therapeutic benefit.
Before your appointment, our care team provides detailed instructions and ensures you’re medically cleared for treatment.
You’ll self-administer Spravato® under clinical supervision, then rest comfortably while our team monitors your response.
After the session, we’ll discuss your experience, track your progress, and provide next-step guidance to optimize long-term results.
Our integrated approach ensures that your physical and emotional, well-being are all supported throughout your journey. With a compassionate team and clear communication every step of the way, we make getting the right care simple, ansd comfortable.

Call us or book online. We’ll help you find a convenient time. Often same-day or next-day—so you can begin prioritizing your mind and body without unnecessary waiting.
During your visit, you’ll meet us and together, we’ll create a personalized plan that addresses both your mental and physical health goals.
Your care doesn’t end after one visit. From follow-ups and prescriptions to ongoing wellness management, our team stays connected to ensure consistent support and lasting results for your body and mind.
Starting Spravato® treatment is an important decision. These answers are designed to help you understand how esketamine therapy works and how it fits into your overall care plan at Lonerock Clinic.
Spravato® is an FDA-approved nasal spray containing esketamine, a derivative of ketamine, used for treatment-resistant depression. Unlike traditional antidepressants that primarily target serotonin, Spravato® works on the brain’s glutamate system to help restore neural connections and may provide faster symptom relief for some patients.
Spravato® is typically recommended for adults with major depressive disorder who have not responded adequately to at least two antidepressant medications. A comprehensive evaluation at Lonerock Clinic helps determine whether Spravato® is appropriate based on your diagnosis, medical history, and previous treatment response.
Spravato® is most effective when used as part of a comprehensive care plan. It is often combined with ongoing medication management, psychotherapy, and lifestyle support. At Lonerock Clinic, treatment is coordinated to ensure Spravato® aligns with your broader mental health goals and long-term stability.
During a Spravato® session, the nasal spray is self-administered under medical supervision in a controlled clinical setting. Patients remain in the clinic for observation for approximately two hours so providers can monitor blood pressure, side effects, and overall response before discharge.
Common side effects include dizziness, nausea, mild increases in blood pressure, and temporary dissociation. These effects typically resolve within a few hours after treatment. Because Spravato® is administered under medical supervision, patients are closely monitored to ensure safety and comfort.